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METHODS AND COMPOSITIONS TO ELICIT MULTIVALENT IMMUNE RESPONSES AGAINST DOMINANT AND SUBDOMINANT EPITOPES, EXPRESSED ON CANCER CELLS AND TUMOR STROMA
专利权人:
发明人:
申请号:
HK12104254.9
公开号:
HK1163705A
申请日:
2012.04.30
申请国别(地区):
HK
年份:
2012
代理人:
摘要:
The present invention provides a method of treating cancer by providing to a subject in need thereof an immunogenic composition comprising a nucleic acid construct encoding a polypeptide comprising CTL epitopes PSMA288-297 and PRAME425-433, or a cross-reactive analogue. In embodiments of the present invention there is provided methods and compositions for inducing, entraining, and/or amplifying the immune response to MHC class-I restricted epitopes of carcinoma antigens to generate an effective anti-cancer immune response.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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