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נגזרות ביארייליות, תכשירי רוקחות המכילים אותן ושימושים בהן
专利权人:
KAKEN PHARMACEUTICAL CO. LTD
发明人:
申请号:
IL25816018
公开号:
IL258160D0
申请日:
2018.03.15
申请国别(地区):
IL
年份:
2018
代理人:
摘要:
Provided is a compound showing excellent antifungal activity against Trichophyton fungus, which is a major causative microorganism of superficial mycosis, and high effectiveness on diseases caused by Trichophyton fungi. A biaryl derivative represented by the formula (I) or a salt thereof: wherein ring A is an optionally substituted phenyl, or an optionally substituted 5- or 6-membered ring heteroaryl (ring A may be further condensed to form an optionally substituted fused ring); Q is CH 2 , C=O, NH, O, S or the like; X 1 , X 2 and X 3 are CR 1 or N; Y is CH or N; Z is CR 2b or N; R 2a and R 2b are each a hydrogen atom, a halogen atom, an optionally substituted C 1 -C 6 alkyl group, a C 1 -C 6 haloalkyl group or the like; R 2a and R 2b may form, together with carbon atoms bonded thereto, an optionally substituted carbocycle, or an optionally substituted heterocycle.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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