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2-pyridinecarboxamide derivative having GK-activating activity
专利权人:
MSD K.K.
发明人:
Asai, Masanori,Nishimura, Teruyuki,Hashimoto, Noriaki,Sagara, Yufu
申请号:
AU2007307560
公开号:
AU2007307560B2
申请日:
2007.10.05
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
Disclosed is a compound represented by the formula (I) or a pharmaceuticallyacceptable salt thereof, which has a glucokinase-activating activity and istherefore useful for the treatment of diabetes or obesity. (I) wherein Rand R independently represent a lower alkyl group; and Xrepresents a group represented by the formula (II-1): (II-1) where Rand R independently represent a hydrogen atom or a lower alkyl group,or R and R together with a nitrogen atom to which Rand R are bonded may form a 4- to 7-membered nitrogenated aliphaticring (wherein one of the carbon atoms constituting the 4- to 7-membered nitrogenatedaliphatic ring may be substituted by an oxygen atom), or R and Rtogether with any carbon atom in the group (CH) may forma 4- to 7-membered nitrogenated aliphatic ring or the like; and m represents aninteger of 1 to 3.
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