The present invention provides an ultrasound three-dimensional (3D) full-body tomography system, comprising an ultrasound guided wave medium container, an ultrasound probe array, and an ultrasound tomography device. The ultrasound guided wave medium container has a detection space, wherein the detection space is filled with a guided wave medium in order for a subject's body to be immersed in the guided wave medium. The ultrasound probe array is provided in the ultrasound guided wave medium container and comprises a plurality of probe units, wherein the probe units are integrated into an annular array and are arranged along a periphery of the detection space. The ultrasound tomography device is for constructing a 3D image model based on data fed back from each pixel of the ultrasound probe array.
