VAN DER GRAAF ADRIANUS CORNELLS,HENNING ROBERT HENK,DEELMAN LEO EDWIN,EUVERINK GERRIT JAN WILLEM
申请号：
IN201747045521
公开号：
IN201747045521A
申请日:
2017.12.19
申请国别(地区):
IN
年份:
2018
代理人:
摘要：
The present invention relates to compounds for prophylaxis or treatment of organ damage by restoring endothelial function and/or inhibiting reactive oxygen species production and especially to compounds for prophylaxis or treatment of diabetic kidney damage. Specifically, the present invention relates to 6-hydroxy-2,5,7,8-tetramethylchroman-2-yl)(piperazin-1-yl)methanone or N,6- dihydroxy-2,5,7,8-tetramethylchroman-2-carboxamide or a pharmaceutically acceptable salt or base thereof for use in the prophylaxis or treatment of organ damage by restoring endothelial function and/or inhibiting reactive oxygen species production and especially diabetic kidney organ damage.
