БРОКАНЬЕР Линда Л. (US),ЧЕН Хелен (US),ЧОБАНИАН Гарри Р. (US),КЛЕМЕНТС Мэттью Дж. (US),КРЕСПО Алехандро (US),ДЕМОНГ Дюан Е. (US),ГО Янь (US),ХАДЖМАНН Уилльям К. (US),МАРКАНТОНИО Карен М. (US),МИЛЛЕР М
申请号：
RU2015140066
公开号：
RU2015140066A
申请日:
2014.02.20
申请国别(地区):
RU
年份:
2017
代理人:
摘要：
Novel compounds of the structural formula (I), and the pharmaceutically acceptable salts thereof, are agonists of G-protein coupled receptor 40 (GPR40) and may be useful in the treatment, prevention and suppression of diseases mediated by the G-protein-coupled receptor 40. The compounds of the present invention may be useful in the treatment of Type 2 diabetes mellitus, and of conditions that are often associated with this disease, including obesity and lipid disorders, such as mixed or diabetic dyslipidemia, hyperlipidemia, hypercholesterolemia, and hypertriglyceridemia.
