The present invention relates to a spawning and proliferation box for the mass proliferation of bees which are pollen vectors. In existing techniques, a spawning box and a proliferation box are separately formed for the mass proliferation of bees, and a spawning dish in the spawning box is moved to the proliferation box in order to raise bees, so labor is needed and bees can be lost while being moved. The excrement or sugar water from bees can be easily stained on the surface of a wooden box. Much labor is needed to remove and wash the stains. To solve the above-described problems, in the present invention, spawning and proliferation can be continuously performed in the same box which is a spawning and proliferation box which is integrally produced using a synthetic resin plate material without separately producing the spawning box and the proliferation box. A queen bee which is to spawn is disposed at a bottom grill (4) installed on the bottom surface of the spawning and proliferation box. A spawning inducin
