KASTRUP, CHRISTIAN,YEON, JU HUN,BAYLIS, JAMES,BURKE, THOMAS FREDERICK
申请号：
CA2937049
公开号：
CA2937049A1
申请日:
2014.10.02
申请国别(地区):
CA
年份:
2015
代理人:
摘要：
A simple, self-propelling particle system is disclosed that can deliver a cargo through flowing aqueous solutions. This disclosure provides a non-aqueous composition comprising: (i) particles formed of a carbonate salt and having an average diameter of about 100 µm or less and (ii) an acid in solid form. The particles may be associated with a cargo molecule or particle. In mouse models of severe hemorrhage, the propelled particles are able to deliver a procoagulant enzyme and halt bleeding.
