The present invention relates to novel salts of rebamipide prodrugs and use thereof. The novel salts of rebamipide prodrugs provided by the present invention have higher in vivo absorption rate when compared with rebamipide. Therefore, the novel salts of rebamipide prodrugs can be used to replace the rebamipide to effectively prevent or treat gastric ulcer, acute gastritis, chronic gastritis, dry eye syndrome, cancers, osteoarthritis, rheumatoid arthritis or obesity.本發明涉及一種瑞巴派特前體藥物之鹽類及其運用,本發明瑞巴派特前體藥物之鹽類與瑞巴派特相比,體內吸收率更優秀,因而可代替瑞巴派特來有效地用於預防或治療胃潰瘍、急性胃炎、慢性胃炎、幹眼綜合征、癌症、骨關節炎、類風濕關節炎或肥胖。