PURPOSE: A pharmaceutical composition containing fish eye extract is provided to effectively treat corneal and conjunctival epithelium disorders without side effects. CONSTITUTION: A composition for treating xerophthalmia contains 0.01-10%(w/v) of fish eye extract as an active ingredient. The composition further contains preservative, isotonic agent, stabilizing agent, antioxidant, or pH adjusting agent. The fish eye extract is prepared at 100-3000Mpa of pressure, 40-90 Deg. C. for 5-60 minutes. The fish eye extract is prepared by macerating, reflux extraction, hot water extraction, ultrasonic wave extraction, and extra-high voltage extraction. [Reference numerals] (AA) Control group； (BB) Comparative embodiment； (CC) Embodiment 1； (DD) Embodiment 2； (EE) Embodiment 3； (FF) Embodiment 4； (GG) Embodiment 5； (HH) Embodiment 6； (II) Unit : hours본 발명은 어류 안구 추출물을 유효성분으로 포함하는 안구건조증 치료용 약제학적 조성물에 관한 것이다.본 발명은 어류 안구 추출물을 사용하여, 기존의 항염증성 약물의 반복 투여에 따른 부작용 없이 각·결막 상피 장애증 등의 안구 질환을 효과적으로 치료할 수 있다.
