1-(4-(benzylbenzamid0) -benzyl) azetidine-3-carboxylic acid derivatives and related compounds as SlP receptor modulators for the treatment of immune disorders
Neira, Susana C.,Yu, Xiang,Burli, Roland,Cee, Victor,Lanman, Brian
申请号：
AU2008302746
公开号：
AU2008302746B2
申请日:
2008.09.19
申请国别(地区):
AU
年份:
2014
代理人:
摘要：
The present invention relates to amides that have activity as SlP receptor modulatingagents and the use of such compounds to treat diseases associated with inappropriateSlP receptor activity. The compounds may be used as immunomodulators, e.g.,for treating or preventing diseases such as autoimmune and related immune disordersincluding systemic lupus erythematosus, inflammatory bowel diseases suchas Crohn's disease and ulcerative colitis, type I diabetes, uveitis, psoriasis,myasthenia gravis, rheumatoid arthritis, non- glomerular nephrosis, hepatitis,Behcet's disease, glomerulonephritis, chronic thrombocytopenic purpura,hemolytic anemia, hepatitis and Wegner's granuloma； and for treatingother conditions.
