Brian Lanman;Victor Cee;Susana C. Neira;Roland Burli;Xiang Yu
发明人:
Susana C. Neira,Xiang Yu,Roland Burli,Victor Cee,Brian Lanman
申请号：
US13327951
公开号：
US20120088749A1
申请日:
2011.12.16
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention relates to amides that have activity as S1P receptor modulating agents and the use of such compounds to treat diseases associated with inappropriate S1P receptor activity. The compounds may be used as immunomodulators, e.g., for treating or preventing diseases such as autoimmune and related immune disorders including systemic lupus erythematosus, inflammatory bowel diseases such as Crohn's disease and ulcerative colitis, type I diabetes, uveitis, psoriasis, myasthenia gravis, rheumatoid arthritis, non-glomerular nephrosis, hepatitis, Behçet's disease, glomerulonephritis, chronic thrombocytopenic purpura, hemolytic anemia, hepatitis and Wegner's granuloma； and for treating other conditions.
