ACID CERAMIDASE INHIBITORS AND THEIR USE AS MEDICAMENTS

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专利权人:

FONDAZIONE ISTITUTO ITALIANO DI TECHNOLOGIA;THE REGENTS OF THE UNIVERSITY OF CALIFORNIA;UNIVERSITA'DEGLI STUDI DI PARMA

发明人:

Daniele Piomelli,Natalia Realini,Marco Mor,Chiara Pagliuca,Daniela Pizzirani,Rita Scarpelli,Tiziano Bandiera

申请号：

US14404226

公开号：

US20150111892A1

申请日:

2013.05.27

申请国别(地区):

US

年份:

2015

代理人:

摘要：

The present invention concerns, in a first aspect, compounds of Formula I as defined herein, pharmaceutically acceptable salts thereof and pharmaceutical compositions containing such compounds. The present invention also relates to compounds of Formula I for use as acid ceramidase inhibitors, and in the treatment of cancer and other disorders in which modulation of the levels of ceramide is clinically relevant.

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