Fondazione Istituto Italiano di Tecnologia;Università degli Studi di Parma;The Regents of the University of California
发明人:
申请号:
EP13739362.5
公开号:
EP2875006B1
申请日:
2013.05.27
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
The present invention concerns, in a first aspect, compounds of Formula I as defined herein, pharmaceutically acceptable salts thereof and pharmaceutical compositions containing such compounds. The present invention also relates to compounds of Formula I for use as acid ceramidase inhibitors, and in the treatment of cancer and other disorders in which modulation of the levels of ceramide is clinically relevant.