The present invention provides: a composition capable of inhibiting reduction of lactic acid bacteria of the genus Lactobacillus in the intestine of a subject to whom an antimicrobial drug is administered and an inhibition method thereof. More specifically, the composition according to the present invention is used for inhibiting reduction of lactic acid bacteria of the genus Lactobacillus in the intestine of a subject to whom an antimicrobial drug is administered, the composition comprising a fermented whey product fermented with a propionic acid bacterium.本發明提供一種於經施予抗菌藥物之對象中,能抑制其腸道內乳桿菌屬乳酸菌減少之組成物及其抑制方法。 更詳細而言,本發明之組成物為一種於經施予抗菌藥物之對象中,抑制其腸道內乳桿菌屬乳酸菌減少用之組合物,其特徵在於,其係包含源自丙酸桿菌之乳清發酵物而成。無