Hsin-Ell WANG,Chien-Chung HSIA,Mao-Chi WENG,Kun-Liang LIN,Hao-Wen KAO,Chao-Cheng CHEN,Kwan-Hwa CHI,Der-Chi TIEN,Wuu-Jyh LIN
申请号：
US15704378
公开号：
US20180117188A1
申请日:
2017.09.14
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention is related to a radiolabeled active targeting pharmaceutical composition, including: a bioconjugate and a radionuclide, wherein the bioconjugate includes a biomolecule and a metal nanoparticle, wherein the biomolecule has an affinity for receptors on the surface of a cell membrane and is selected from the group consisting of a peptide and a protein. The present invention further provides a method for evaluating a thermal adjuvant therapy for tumors and a kit thereof. The above-mentioned pharmaceutical composition is applied to evaluate a tumor accumulation time, so as to establish the optimal policy for a radiofrequency- or laser-induced thermal adjuvant therapy for tumors.
