Hsin-Ell Wang,Chien-Chung Hsia,Mao-Chi Weng,Kun-Liang Lin,Hao-Wen Kao,Chao-Cheng Chen,Kwan-Hwa Chi,Der-Chi Tien,Wuu-Jyh Lin
申请号：
US14490072
公开号：
US09789214B2
申请日:
2014.09.18
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present invention is related to a radiolabeled active targeting pharmaceutical composition, including: a bioconjugate and a radionuclide, wherein the bioconjugate includes a biomolecule and a metal nanoparticle, wherein the biomolecule has an affinity for receptors on the surface of a cell membrane and is selected from the group consisting of a peptide and a protein. The present invention further provides a method for evaluating a thermal adjuvant therapy for tumors and a kit thereof. The above-mentioned pharmaceutical composition is applied to evaluate a tumor accumulation time, so as to establish the optimal policy for a radiofrequency- or laser-induced thermal adjuvant therapy for tumors.
