Federico Mailland,Michela Legora,Simone Del Sordo,Stefania Gagliardi
申请号：
BR112012015732
公开号：
BR112012015732A2
申请日:
2010.12.28
申请国别(地区):
BR
年份:
2019
代理人:
摘要：
hydroxy quinoline compound and pharmaceutical formulation. The present invention provides further secondary 8-hydroxy-quinoline-7-carboxamide derivatives of formula (I) and pharmaceutically acceptable salts thereof. These compounds are useful as antifungal agents. specifically, these compounds have been tested against tricophyton rubrum, tricohyton emntagrophytes, aspergillus niger and brevicaulis scopulariopsis. Many of these compounds are active against candida species such as candida albicans and candida glabrata.composto de hidróxi-quinolina e formulação farmacêutica. a presente invenção fornece nosvos derivados de 8-hidróxi-quinolina-7-carboxamida secundários de fórmula (i) e sais farmaceuticamente aceitáveis destes. estes compostos são úteis como agentes antifúngicos. especificamente, estes compostos foram testados contra tricophyton rubrum, tricohyton emntagrophytes, aspergillus niger e brevicaulis scopulariopsis. muitos detses compostos são ativos contra espécies de candida, tais como candida albicans e candida glabrata.
