FEDERICO MAILLAND,MICHELA LEGORA,SIMONE DEL SORDO,STEFANIA GAGLIARDI
申请号：
BR112012015735
公开号：
BR112012015735A2
申请日:
2010.12.28
申请国别(地区):
BR
年份:
2016
代理人:
摘要：
hydroxy quinoline compound. The present invention provides 8-hydroxy-quinoline-7-carboxamide secondary derivatives of formula (I) and pharmaceutically acceptable salts thereof. These compounds are useful as antifungal agents. Specifically, these compounds were tested against tricofyton rubrum, tricofyton mentagrofytes, aspergillus niger and brevicaulis scopulariopsis. These compounds are active against candida species such as candida albicans and candida glabrata.composto de hidroxi-quinolina. a presente invenção fornece derivados secundários de 8-hidróxi-quinolina-7--carboxamida de fórmula geral (i) e sais farmaeuticamente aceitáveis destes. estes compostos são úteis como agentes antifúngicos. especificamente, estes compostos foram testados contra tricofyton rubrum, tricofyton mentagrofytes, aspergillus niger e brevicaulis scopulariopsis. estes compostos são ativos contra espécies de candida, tais como candida albicans e candida glabrata.
