Anti-PD-L1/anti-PD-1 natural antibody structure-like heterodimeric bispecific antibody and preparation thereof

• 收藏
• 分享

专利权人:

Ltd.;Beijing Hanmi Pharm. Co.

发明人:

Liu, Jiawang,Song, Nanmeng,Yang, Yaping,Jin, Mengxie

申请号：

AU2018243104

公开号：

AU2018243104A1

申请日:

2018.03.28

申请国别(地区):

AU

年份:

2019

代理人:

摘要：

Provided are an anti-PD-L1/anti-PD-1 natural antibody structure-like heterodimeric bispecific antibody and a preparation thereof. In particular, provided are a highly stable heterodimeric anti-PD-L1/anti-PD-1 bispecific antibody with characteristics of a natural IgG and without mismatched heavy chain-light chain, and a preparation thereof. The bispecific antibody can bind to both target molecules and is more effective in treating a complex disease.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/