Korea Research Institute of Chemical Technology;Korea Advanced Institute of Science and Technology
发明人:
KIM, Ki-Suk,LEE, Hyang-Ae,PARK, Sun Hyun,LEE, Haeshin,SHIN, Mikyung
申请号:
AU2019237720
公开号:
AU2019237720A1
申请日:
2019.03.12
申请国别(地区):
AU
年份:
2020
代理人:
摘要:
The present invention relates to a cardiac targeting agent comprising tannic acid, which, by TANNylating a heart disease therapeutic agent to be delivered to the heart, provides the heart disease therapeutic agent with the ability to bind to the cardiac myocardium, thus enabling cardiac targeting and accumulation of the therapeutic agent, wherein the therapeutic agent can be targeted to the heart with high efficiency even via non-invasive intravenous administration alone, unlike conventional invasive methods used to target therapeutic agents to the heart.