KIM, YONG SOOKR,김용수,BAEK, YOUNG MIKR,백영미,LEE, SOO HYUNGKR,이수형,HAN, JIN TAEKKR,한진택,JUNG, TAEK GEUNKR,정택근,KIM, WAN YOUNGKR,김완영,SIM, TAE KYUNGKR,심태경,JANG, SUNG ILKR,장성일,JEON, YONG WOOKR,전용우,LEE, SOO JUNG
申请号：
KR1020140099313
公开号：
KR1014819430000B1
申请日:
2014.08.01
申请国别(地区):
KR
年份:
2015
代理人:
摘要：
The present invention relates to a method for preparing an extract of Lithosperumum erythrorhizon, capable of providing a novel, economical, and eco-friendly extraction method by not using an organic solvent such as chloroform, benzene, nucleic acid, etc. and requiring no high-priced production facilities. The method for preparing an extract of Lithosperumum erythrorhizon of the present invention comprises: a Lithosperumum erythrorhizon pulverization step (S10) of pulverizing Lithosperumum erythrorhizon a first reflux extraction step (S20) of mixing the pulverized Lithosperumum erythrorhizon with ethanol and a surfactant, followed by reflux extraction at a boiling point of ethanol, to produce a first extract, wherein the ethanol has a 5- to 10-fold weight of Lithosperumum erythrorhizon and the surfactant has a 0.0001- to 0.001-fold weight of the ethanol a first vacuum concentration step (S30) of filtering the first extract produced in the first reflux extraction step (S20), and vacuum-concentrating the filtrate to produce a first concentrate a second reflux extraction step (S40) of mixing the first concentration produced in the first vacuum concentration step (S30) with ethanol and oil, followed by reflux extraction at a boiling point of ethanol, to a second extract, wherein the ethanol has a 5- to 10-fold weight of the pulverized Lithosperumum erythrorhizon and the oil has a 2- to 10-fold weight of the first concentrate a second vacuum concentration step (S50) of vacuum-concentrating the second extract produced in the second reflux extraction step (S40) to produce a second concentrate and an oil extraction step (S60) of allowing the second concentrate to stand, and then removing an aqueous layer of the second concentrate, thereby producing oil containing sihkonin.COPYRIGHT KIPO 2015본 발명은 자초 추출물의 제조 방법은 인체에 유해한 클로로포름, 벤젠, 핵산 등과 같은 유기 용제를 사용하지 않으면서도, 고가의 생산 설비가 요구되지 않아, 경제적이고, 친환경적인 새로운 추출 방법에 관한 것이다.본 발명의 자초 추출물의 제조 방법은 자초를 분쇄하는 자초분쇄단계(S10)와, 분쇄된 자초에 분쇄된 자초 중량 대비 5
