PROBLEM TO BE SOLVED: To provide a medicinal composition containing pyrrolo[2,3-d]pyrimidine compound having GPR119 receptor agonist activity or a pharmacologically acceptable salt thereof as an active ingredient.SOLUTION: The medicinal composition contains the compound represented by formula [I] [wherein, E is a group represented by the formula: -NH- or the like ring A is a 6-membered aromatic ring which may contain one to two nitrogen atoms as hetero atoms (the aromatic ring may be substituted with a group represented by halogen, -CONRaRb or the like and Ra and Rb are the same or different and each hydrogen, alkyl, hydroxyalkyl or the like) R1 is acyl or the like and R2 is halogen or cyano], or the pharmacologically acceptable salt thereof as the active ingredient.COPYRIGHT: (C)2012,JPO&INPIT【課題】本発明は、GPR119受容体アゴニスト作用を有するピロロ[2,3-d]ピリミジン化合物又はその薬理的に許容し得る塩を有効成分とする医薬組成物を提供する。【解決手段】下記式[I]:〔式中、Eは式:-NH-で示される基等、環Aはヘテロ原子として1~2個の窒素原子を含有していてもよい6員芳香環(該芳香環はハロゲン、式:-CONRaRbで示される基等で置換されていてもよい)、Ra及びRbは同一又は異なって水素、アルキル、ヒドロキシアルキル等)R1はアシル等、R2はハロゲン又はシアノを表す。〕で示される化合物又はその薬理的に許容し得る塩を有効成分としてなる医薬組成物。【選択図】なし
