PROBLEM TO BE SOLVED: To provide a quinazoline compound having GPR119 receptor agonistic activity and being useful as a medicine.SOLUTION: There is provided a compound represented by general formula [I] or a pharmacologically acceptable salt thereof. (In formula [I], R1 represents hydrogen or a halogen ring A represents a 6-membered aryl ring which may contain nitrogen R01 represents hydrogen, a halogen, alkylthio or the like R02 represents hydroxy or the like R2 represents (a) cyano, or (b) 5 to 6-membered heteroaryl which contains one to three heteroatoms selected from oxygen and nitrogen, and which may be substituted with alkyl or the like which may be substituted with one to three halogens).COPYRIGHT: (C)2013,JPO&INPIT【課題】GPR119受容体アゴニスト作用を有し、医薬として有用なキナゾリン化合物を提供する。【解決手段】一般式[I]:〔式中、R1は水素又はハロゲン、環Aは窒素原子を含有していてもよい6員芳香族環式基、R01は水素、ハロゲン、アルキルチオ等、R02は水酸基等、R2は(a)シアノ、又は(b)酸素及び窒素から選ばれる1~3個のヘテロ原子を含有し、かつ1~3個のハロゲンで置換されていてもよいアルキル等で置換されていてもよい5~6員へテロアリールを表す。〕で示される化合物またはその薬理的に許容し得る塩。【選択図】なし
