Axel Pleschke,Thomas Schmidt,Joachim Gebhardt,Sandra Loehr,Michael Keil,Jan Hendrik Wevers
申请号：
US12681843
公开号：
US09920002B2
申请日:
2008.10.10
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention relates to a process for preparing sulfuric diamides of the general formula IR1R2N—S(O)2—NH2 (I)in which R1 and R2 are each independently a primary alkyl radical having from 1 to 8 carbon atoms, a secondary alkyl radical having from 3 to 8 carbon atoms or a cycloalkyl radical having from 5 to 8 carbon atoms, or, together with the nitrogen atom, form a 5- to 8-membered, saturated nitrogen heterocycle which, as well as the nitrogen atom, may have a further heteroatom selected from O and S as a ring member, where the nitrogen heterocycle is unsubstituted or may have 1, 2, 3 or 4 alkyl groups having in each case from 1 to 4 carbon atoms as substituents. The process comprises the following steps:i) the reaction of a secondary amine of the formula IIR1R2NH (II) in which R1 and R2 are each as defined above with sulfuryl chloride in an inert solvent, especially an aromatic solvent, in the presence of a tertiary amine to give a sulfamoyl chloride of the formula IIIR1R2N—S(O)2—Cl (III) in which R1 and R2 are each as defined above, andii) reaction of the sulfamoyl chloride of the formula III obtained in step i) with ammonia,the sulfamoyl chloride of the formula III being used in step ii) in the form of the solution obtained in step i) in the inert solvent, especially the aromatic solvent.
