PROBLEM TO BE SOLVED: To provide a therapeutic agent for autoantibody-dependent autoimmune diseases that can maintain an immune response to an external antigen.SOLUTION: The present invention provides a therapeutic agent for autoantibody-dependent autoimmune diseases or a pathology progress inhibitor, which contains an expression inhibitory substance that inhibits the expression of NR4A2 gene, or a function inhibitory substance that inhibits the functions of NR4A2 protein, as active ingredients.SELECTED DRAWING: NoneCOPYRIGHT: (C)2019,JPO&INPIT【課題】外部抗原への免疫応答を維持できる、自己抗体依存性自己免疫疾患の治療剤を提供すること。【解決手段】NR4A2遺伝子の発現を抑制する発現抑制物質、又はNR4A2タンパクの機能を抑制する機能抑制物質を有効成分として含有する、自己抗体依存性自己免疫疾患の治療剤又は病態の進行抑制剤。【選択図】なし
