The present invention relates to a composition comprising: a) at least 70% by weight of at least one pharmaceutically active substance which is a mixture of chondroitin sulphate and glucosamine or pharmaceutically acceptable salts thereof b) 5 to 25% by weight of at least one binder, where at least 30% by weight of the binder has a particle size less than 70 µm c) 0.1 to 0.75% by weight of at least one filler, where at least 90% by weight of the filler has a particle size less than 1.5 µm and d) optionally further additives, where the total fraction of constituents in the composition is 100% by weight, and also to an oral administration form comprising the composition.