An external end device for permanent catheters includes a container that houses two taps being provided with knobs and having, at one hand, a first connector for the connection to the catheters and, at the other hand, second connectors projecting from the container for the connection to an external equipment. The first connector is connected to the catheter by a coupling exiting the container and externally holding a subcutaneous cuff designed to be positioned in the subcutaneous tissue of the patient's body. The second connectors are provided with caps surrounded by the disposable absorbent material being received in the closure lid and having spaces for housing the caps for protecting them externally from a bacterial attack by the antiseptic substance by which it is impregnated. Further an implantation method of the device in a patient is disclosed.