An external end device for permanent catheters comprises a container (5) thathouses two taps (26, 27) being providedwith knobs (8, 9) and having, at one hand, a first connector (23) for theconnection to the catheters (2) and, at the otherhand, second connectors (12, 13) projecting from the container for theconnection to an external equipment. The first connector(23) is connected to the catheter (2) by a coupling (4) exiting the container(5) and externally holding a subcutaneous cuff (3)designed to be positioned in the subcutaneous tissue of the patient's body.The second connectors (12, 13) are provided with caps(14, 15) surrounded by the disposable absorbent material (73) being receivedin the closure lid (20) and having spaces (16, 17) forhousing the caps for protecting them externally from a bacterial attack bymeans of the antiseptic substance by which it is impregnated.Further an implantation method of the device in a patient is disclosed.