YI, So Yoen;이의진;정봉현;KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY;한국생명공학연구원;이소연;CHUNG, Bong Hyun;LEE, Ui Jin
发明人:
CHUNG, Bong Hyun,정봉현,YI, So Yoen,이소연,LEE, Ui Jin,이의진
申请号：
KRKR2012/005129
公开号：
WO2013/024968A1
申请日:
2012.06.28
申请国别(地区):
KR
年份:
2013
代理人:
摘要：
The present invention relates to a novel compound isolated from quamoclit, and to a composition containing the compound as an active ingredient, and more particularly, to a novel compound isolated from quamoclit, and to a composition for preventing or treating diabetes or diabetic complications containing the compound as an active ingredient. The novel compound derived from quamoclit according to the present invention has superior effects of reducing blood glucose levels, promoting insulin secretion, inhibiting VEGF expression, etc., and thus is effective in preventing or treating diabetes and various diabetic complications and further promotes treatment effects when administered in combination with conventional diabetes treatment agents.La présente invention concerne un nouveau composé isolé à partir de quamoclit, et une composition contenant le composé en tant que substance active, et plus particulièrement, un nouveau composé isolé à partir de quamoclit, et une composition pour prévenir ou traiter le diabète ou des complications diabétiques contenant le composé en tant que substance active. Le nouveau composé dérivé de quamoclit selon la présente invention a des effets supérieurs de réduction de la glycémie, induction de la sécrétion d'insuline, inhibition de l'expression de VEGF, etc., et est donc efficace dans la prévention ou le traitement du diabète et de différentes complications diabétiques et induit en outre des effets de traitement lorsqu'il est administré en combinaison avec des agents de traitement du diabète conventionnels.본 발명은 유홍초속에서 분리한 신규화합물 및 이를 유효성분으로 포함하는 조성물에 관한 것으로, 보다 상세하게는, 유홍초속에서 분리한 신규화합물 및 이를 유효성분으로 함유하는 당뇨병 또는 당뇨합병증의 예방 또는 치료용 조성물에 관한 것이다. 본 발명에 따른 유홍초속 유래 신규화합물은 우수한 혈당강하, 인슐린 분비촉진, VEGF 발현 저해 등의 효과를 가지고 있어, 당뇨병 및 이로 인한 각종 합병증의 예방 또는 치료에 효능을 가질 뿐만 아니라, 기존 당뇨병치료제와 병행투여시 치료효과를 촉진시킬 수 있다.
