HOTTER, Andreas,GRIESSER, Ulrich,ADAMER, Verena,LANGES, Christoph
申请号：
EPEP2011/060630
公开号：
WO2011/161245A3
申请日:
2011.06.24
申请国别(地区):
EP
年份:
2012
代理人:
摘要：
The present invention relates to crystalline form I of Febuxostat as well as to pharmaceutical compositions comprising crystalline form I as an active pharmaceutical ingredient. Furthermore the present invention relates to a further polymorphic form of Febuxostat designated as form II and to a novel solvate of Febuxostat. The present invention also relates to methods of making crystalline form I, form II and the novel solvate of Febuxostat.Cette invention concerne la forme cristalline I du Fébuxostat ainsi que des compositions pharmaceutiques la contenant à titre de substance pharmaceutique active. Cette invention concerne, en outre, une autre forme polymorphe du Fébuxostat, appelée forme II, et un nouveau solvate de Fébuxostat, ainsi que des procédés de préparation de ladite forme cristalline I, de ladite forme II et dudit nouveau solvate de Fébuxostat.
