Oda, Shannon K.,Greenberg, Philip D.,Schmitt, Thomas M.
申请号:
AU2018236461
公开号:
AU2018236461A1
申请日:
2018.03.16
申请国别(地区):
AU
年份:
2019
代理人:
摘要:
The present disclosure relates to immunomodulatory fusion proteins containing an extracellular binding domain and an intracellular signaling domain, wherein binding of a target can generate a modulatory signal in a host cell, such as a T cell. The present disclosure also relates to uses of immune cells expressing such immunomodulatory fusion proteins to treat certain diseases, such as cancer or infectious disease.