The invention relates to a smart thermal insulation box, including thermally insulated layers with mitered edges forming a thermally insulated space, and said space surrounded by corrugated material. The box also has externally viewable and operable temperature and humidity sensors, and optionally, a vibration sensor, where the sensors are preferably fixed inside the box to one side. One of the cardboard panels forming the top of the box which overlays the insulation layer has a window configured to overlay the display panel. An audible alert system may also be included to alert users to temperature or humidity excursions.
