A treatment instrument lifting adjusting portion 19 including a lifting member 65 and an operation wire 66 is disposed outside of a treatment instrument guiding-out path including an exit member 60 and a tube 61 in a distal end portion 11. Thus, cleaning work can be performed by inserting, for example, a brush into the treatment instrument guiding-out path, and is easily performed similarly to an endoscope of a type having no treatment instrument lifting function.