PROBLEM TO BE SOLVED: To provide a substance capable of binding to an EGFR (Epidermal Growth Factor Receptor) specifically with a high affinity, and a medicinal agent comprising the substance.SOLUTION: Provided is a peptide which comprises at least the amino acid sequence represented by following formula and is composed of 12 to 50 amino acids, wherein formula (1) is X-His-X-X-Asp-X-X-X-X-X-Trp-His, in which Xrepresents Trp or the like, Xrepresents Leu or the like, Xrepresents Ser or the like, Xrepresents Leu or the like, Xrepresents Trp or the like, Xrepresents Gln or the like, Xrepresents Asn or the like, and Xrepresents Ala or the like.【課題】EGFR（上皮成長因子受容体）に特異的かつ高親和性で結合する物質及びそれを含む医薬の提供。【解決手段】少なくとも下記式で表されるアミノ酸配列を有するアミノ酸数12～50のペプチド。X1-His-X2-X3-Asp-X4-X5-X6-X7-X8-Trp-His(1)（式(1)中、X1はTrpなどを示し、X2はLeuなどを示し、X3はSerなどを示し、X4はLeuなどを示し、X5はTrpなどを示し、X6はGlnなどを示し、X7はAsnなどを示し、X8はAlaなどを示す。）【選択図】なし
