Provided are: a substance capable of binding to an EGFR specifically with a high affinity and a medicinal agent comprising the substance.A peptide which comprises at least the amino acid sequence represented by formula (1), (2) or (3) and is composed of 12 to 50 amino acid residues.X1-His-X2-X3-Asp-X4-X5-X6-X7-X8-Trp-His (1)(In formula (1), X1 represents Trp or Phe X2 represents Leu, Met, Ile or Val X3 represents Ser, Ala, Thr, Gly, Asn, Asp, Glu, Arg or Lys X4 represents Leu, Met, Ile, Val, Ala, Phe, Tyr, Trp, His or Cys X5 represents Trp, Phe or Tyr X6 represents Gln, Asn, Asp, Glu, Ala, Ser, Thr, Leu, Met, Lys or Arg X7 represents Asn, Gln, Asp, Glu, Ser, Thr, Ala, Gly, Lys or Arg and X8 represents Ala, Gly, Ser, Thr, Asn, Val or Cys.)Phe-His-Asp-Trp-X11-Pro-X12-X13-X14-X15-X16-X17 (2)(In formula (2), X11 represents Leu, Met, Ile, Val, Ala, Phe, Tyr, Trp, His or Cys X12 represents Glu, Asp, Gln, Asn, Ala, Ser, Thr, Lys, Arg or His X3 represents Val, Ala, Leu, Ile, Met, Thr, Cys or Asn X14 represents Ser, Ala, Thr, Gly, Asn, Asp, Glu, Arg or Lys X5 represents Pro, Val, Ile, Lys, Ala, Met, Trp, Tyr, Ser, Thr, Cys or Phe X16 represents Pro, Val, Ile, Lys, Ala, Met, Trp, Tyr, Ser, Thr, Cys or Phe and X17 represents Asp, Glu, Asn, Gln, Ala, Ser, Thr, Lys, Arg or His.)Leu-His-X21-Ser-X22-Trp-Met-X23-X24-X25-X26-X27 (3)(In formula (3), X21 represents Gln, Asn, Asp, Glu, Ala, Ser, Thr, Leu, Met, Lys or Arg X22 represents Glu, Asp, Gln, Asn, Ala, Ser, Thr, Lys, Arg or His X23 represents Tyr, Phe, Trp, His, Leu, Met, Ile, Val, Cys or Ala X24 represents Val, Ala, Leu, Ile, Met, Thr, Cys or Asn X25 represents Asp, Glu, Asn, Gln, Ala, Ser, Thr, Lys, Arg or His X26 represents Ile, Val, Leu, Met, Ala, Phe, Tyr, Trp or Gly and X27 represents His, Tyr, Phe, Lys, Arg, Leu, Met or Ala.)Linvention concerne : une substance apte à se lier à un EGFR spécifiquement avec une affinité élevée et un agent médicinal comprenant la substance. Linvention concerne un peptide qui comprend au moi
