When designating the decrease salt as purpose, it is possible to offer the saltiness reinforcement medicine which makes that insufficiency of saltiness is compensated for possible and is superior. The dipeptide which includes glutamic acid, concrete, protein material enzyme disassembly ones and/or adding Glu-Ala, Glu-Arg, Glu-Asn, Glu-Asp, Glu-Gln, Glu-Glu, Glu-Gly, Glu-His, Glu-Ile, Glu-Leu, Glu-Lys, Glu-Pro, Glu-Ser, Glu-Thr, Glu-Trp, Glu-Tyr, Glu-Val, Arg-Glu, Asn-Glu, Asp-Glu, Gln-Glu, His-Glu, Pro-Glu, Ser-Glu, Thr-Glu and Trp-Glu to basic amino acid and the especially arginine, the saltiness reinforcement medicine which can. These production methods, reinforcement method of the saltiness which uses these, and the eating and drinking item which contains these saltiness reinforcement medicines.減塩を目的とした時の塩味の不足を補うことを可能とする優れた塩味増強剤を提供することができる。グルタミン酸を含むジペプチド、具体的には、Glu-Ala、Glu-Arg、Glu-Asn、Glu-Asp、Glu-Gln、Glu-Glu、Glu-Gly、Glu-His、Glu-Ile、Glu-Leu、Glu-Lys、Glu-Pro、Glu-Ser、Glu-Thr、Glu-Trp、Glu-Tyr、Glu-Val、Arg-Glu、Asn-Glu、Asp-Glu、Gln-Glu、His-Glu、Pro-Glu、Ser-Glu、Thr-Glu、Trp-Gluを蛋白素材酵素分解物及び/又は塩基性アミノ酸、特にアルギニンに添加して得られる塩味増強剤。これらの製造方法、これらを用いた塩味の増強方法、及びこれらの塩味増強剤を含有する飲食品。