FENG, JIANWEN,LOKE, PUI LENG,MONTALBETTI, CHRISTIAN A. G. N.,STABEN, STEVEN
申请号：
TW101108940
公开号：
TW201247650A
申请日:
2012.03.15
申请国别(地区):
TW
年份:
2012
代理人:
摘要：
The invention relates to novel compounds of Formula I: wherein A, Y, R1, R2 and the subscript b each has the meaning as described herein and compounds of Formula I, and stereoisomers, geometric isomers, tautomers, solvates, metabolites, isotopes, pharmaceutically acceptable salts, or prodrugs thereof. Compounds of Formula I and pharmaceutical compositions thereof are useful in the treatment of disease and disorders in which undesired or over-activation of NF-kB signaling is observed.
