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GLYCOSYLATED REPEAT-MOTIF-MOLECULE CONJUGATES
专利权人:
F. HOFFMANN-LA ROCHE AG
发明人:
申请号:
IL20120218911
公开号:
IL218911(D0)
申请日:
2012.03.28
申请国别(地区):
以色列
年份:
2012
代理人:
摘要:
Herein are reported glycosylated repeat-motif-molecule conjugate of the following formula: (repeat-motif-molecule−linkern)m−conjugation partner−(linkero−repeat-motif-molecule)p, wherein n and o are independently of each other and independently for each value of m and p integer values of 0 or 1, and m and p are independently of each other integer values of 0 or 1 or 2 or 3 or 4 or 5 or 6 or 7, and wherein the repeat-motif-molecule conjugate comprises at least one oligosaccharide attached to a glycosylation site. Also reported are encoding nucleic acids and method for producing these repeat-motif-conjugates in mammalian cells.
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