A micro-rna family that modulates fibrosis and uses thereof

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专利权人:

BOARD OF REGENTS THE UNIVERSITY OF TEXAS SYSTEM

发明人:

OLSON ERIC,VAN ROOIJ EVA

申请号：

NZ61479108

公开号：

NZ614791A

申请日:

2008.07.31

申请国别(地区):

NZ

年份:

2015

代理人:

摘要：

Disclosed is the use of an antisense oligonucleotide for preparation of a medicament for treating one or more soft plaques in a vessel wall of a subject, wherein the antisense oligonucleotide comprises a sequence that is at least partially complementary to a miR-29a, miR-29b, and/or miR-29c sequence, and wherein the medicament converts one or more soft plaques to fibrotic tissue.

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