Martin Kruger;Holger Siebeneicher;Michael Reinhardt;Jessica Lohrke;Markus Berger
发明人:
Markus Berger,Martin Kruger,Jessica Lohrke,Michael Reinhardt,Holger Siebeneicher
申请号:
US14239065
公开号:
US09345793B2
申请日:
2012.08.17
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention relates to novel fluorine containing compounds, methods for their preparation, the intermediates of the synthesis, their use as diagnostic agents, especially for imaging of thrombi. The invention relates to positron emission tomography (PET) agents and associated precursor reagents, and methods for producing such radiolaveled agents for imaging of thrombi in a mammalian body. More particularly, the invention relates to small nonpeptide, high-affinity, specific-binding glycoprotein 11b/IIIa antagonists for imaging of thrombi.