Markus Berger,Martin Kruger,Jessica Lohrke,Michael Reinhardt,Holger Siebeneicher
申请号:
US15003368
公开号:
US09744252B2
申请日:
2016.01.21
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention relates to novel fluorine containing compounds, methods for their preparation, the intermediates of the synthesis, their use as diagnostic agents, especially for imaging of thrombi. The invention relates to positron emission tomography (PET) agents and associated precursor reagents, and methods for producing such radiolaveled agents for imaging of thrombi in a mammalian body. More particularly, the invention relates to small nonpeptide, high-affinity, specific-binding glycoprotein IIb/IIIa antagonists for imaging of thrombi.