L'acétonide de triamcinolone cristalline produit par un procédé de broyage

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专利权人:

Aventis Pharma Limited

发明人:

申请号：

EP02079497.0

公开号：

EP1338273B1

申请日:

1999.12.01

申请国别(地区):

EP

年份:

2017

代理人:

摘要：

The present invention is a method of milling materials to form a fine powder with a median particle size below 10 micrometer which is suitable for inhalation and which has substantially no amorphous content generated during milling. The method is particularly suitable for milling materials which are soft. The method comprises milling the material in a fluid energy mill at reduced temperature using helium, or helium mixed with another gas, as milling fluid. Temperatures of -30 DEG C or less are used.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/