Authelin, Jean-Rene, c/o Rhone-Poulenc Rorer SA,Hosek, Patrick, Rhone-Poulenc Rorer SA
申请号:
DK02079497
公开号:
DK1338273T3
申请日:
1999.12.01
申请国别(地区):
DK
年份:
2017
代理人:
摘要:
The present invention is a method of milling materials to form a fine powder with a median particle size below 10 micrometer which is suitable for inhalation and which has substantially no amorphous content generated during milling. The method is particularly suitable for milling materials which are soft. The method comprises milling the material in a fluid energy mill at reduced temperature using helium, or helium mixed with another gas, as milling fluid. Temperatures of -30 DEG C or less are used.