9-CYCLOPENTYL-9H-PURINES À DISUBSTITUTION EN POSITION 2 ET 6, LEUR UTILISATION EN TANT QUE MÉDICAMENTS, ET COMPOSITIONS PHARMACEUTIQUES

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专利权人:

Univerzita Palackého v Olomouci

发明人:

申请号：

EP18720082.9

公开号：

EP3601287A1

申请日:

2018.03.19

申请国别(地区):

EP

年份:

2020

代理人:

摘要：

The present invention relates to novel 2,6-disubstituted-9-cyclopentyl-9H-purines of general formula I, capable of inhibiting the activity of kinases such as FLT3, CDKs and PDGFRs in cancer and other related proliferative diseases. The invention further includes pharmaceutical compositions containing the 2,6-disubstituted-9-cyclopentyl-9H-purines. Compounds of the present invention can be used as active ingredients of a pharmaceutical compositions for treating acute myeloid leukemia (AML).

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中国工程科技知识中心

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