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PEPTIDES IMPARTING CELL PERMEABILITY TO LIPID MEMBRANE STRUCTURE
专利权人:
发明人:
申请号:
EP10837604.7
公开号:
EP2514760B1
申请日:
2010.12.14
申请国别(地区):
EP
年份:
2015
代理人:
摘要:
Provided are peptides imparting cell permeability to a lipid membrane structure and/or enhancing the cell permeability of a lipid membrane structure, and a lipid membrane structure which comprises, as a constituent lipid, a lipid bound to such a peptide and has cell permeability or shows enhanced cell permeability. The amino acid sequences of the peptides imparting cell permeability to a lipid membrane structure and/or enhancing the cell permeability of a lipid membrane structure are represented by: LX 1 X 2 X 1 X 1 X 1 L, LLX 2 X 1 X 1 X 1 L and LX 1 X 2 X 1 X 1 L (wherein L represents a leucine residue X 1 represents a polar amino acid residue and X 2 represents a polar, non-charged and branched chain amino acid residue).
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