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CARRIER FOR INTRACELLULAR DELIVERY OF FUNCTIONAL PROTEIN
专利权人:
发明人:
Hideyoshi Harashima,Yuma Yamada,Sandra Milena Vergara Perez,Yukari Yasuzaki
申请号:
US14385634
公开号:
US20150140066A1
申请日:
2012.09.19
申请国别(地区):
US
年份:
2015
代理人:
摘要:
A liposome comprising a lipid covalently bonded with a polyarginine peptide consisting of 4 to 20 continuous arginine residues and a lipid covalently bonded with a GALA peptide consisting of the amino acid sequence of SEQ ID NO: 1 and/or an R-GALA peptide consisting of the amino acid sequence of SEQ ID NO: 2 as component lipids of lipid membrane, and having a lipid membrane in which a protein to be intracellularly delivered is non-covalently bound to outer surface of the membrane, which is for quickly and conveniently deriver a functional protein, especially such a protein having a high molecular weight, into a cell.
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