The invention concerns a compound of the Formula I wherein m is 0-2 and each R1 is a group such as hydroxy, halogeno, trifluoromethyl heterocyclyl and heterocyclyloxy； R2 is halogeno, trifluoromethyl or (1-6C)alkyl； R3 is hydrogen, halogeno or (1-6C)alkyl； and R4 is (3-6C)cycloalkyl；or pharmaceutically-acceptable salts thereof； processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of diseases or medical conditions mediated by cytokines.本發明係關於式I之化合物其中m為0-2且各R1為諸如羥基、鹵基、三氟甲基、雜環基及雜環氧基之基團；R2為鹵基、三氟甲基或(1-6C)烷基；R3為氫、鹵基或(1-6C)烷基；且R4為(3-6C)環烷基；或其醫藥學上可接受之鹽；製備其之方法，含有其之醫藥組合物及其在治療藉由細胞激素調節之疾病或醫學病症中之用途。
