Inhibitors of S-adenosyl-L-methionine decarboxylase

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专利权人:

Yibin Xiang

发明人:

Yibin Xiang,Bradford Hirth,Cassandra Celatka

申请号：

US12664628

公开号：

US08633168B2

申请日:

2008.06.13

申请国别(地区):

US

年份:

2014

代理人:

摘要：

Novel mechanism-based inhibitors of S-adenosyl-L-methionine decarboxylase are provided. These compounds of formula (1) inhibit the life cycle of trypanosomes, and are useful to treat subjects infected with African trypanosomes. The invention includes pharmaceutical compositions and methods of using the compounds of formula (1).

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中国工程科技知识中心

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http://www.ckcest.cn/home/