F. HOFFMANN-LA ROCHE AG;CHUGAI SEIYAKU KABUSHIKI KAISHA
发明人:
MORICHIKA, TOSHIYUKI,KAMEOKA, DAISUKE,IMAEDA, YOSHIMI,MAEDA, TERUTOSHI,STAUCH, OLIVER BORIS
申请号:
NZ58637808
公开号:
NZ586378A
申请日:
2008.12.26
申请国别(地区):
NZ
年份:
2012
代理人:
摘要:
Disclosed is a stable antibody-containing liquid formulation comprising 40 to 1000 mM arginine and 10 to 200mM methionine. Further disclosed is a method for inhibiting dimerization of molecules of an antibody in a liquid formulation containing the antibody, comprising adding arginine and methionine to the liquid formulation.